Which effect is associated with GLP-1 in addition to stimulating insulin secretion?

• A. Suppresses glucagon and slows gastric emptying.
• B. Increases glucagon secretion.
• C. Accelerates gastric emptying.
• D. Inhibits insulin secretion.

Answer: (A)

GLP-1 has several actions that help control glucose beyond boosting insulin release. It lowers hepatic glucose production by suppressing glucagon, and it slows gastric emptying, which slows the rate at which glucose enters the bloodstream after a meal. Together, these effects help blunt postprandial glucose rises.

So the effect of suppressing glucagon and slowing gastric emptying is the best match for GLP-1 in addition to stimulating insulin secretion. The other options describe actions opposite to GLP-1’s known effects: increasing glucagon would raise glucose production, accelerating gastric emptying would quicken glucose entry, and inhibiting insulin secretion would counter GLP-1’s insulinotropic action.